The Lyme Genes Responsible for Severe Symptoms_1

Lyme disease was first identified in 1975, in Lyme, Conn., but scientists still have more questions than answers about how the bacteria responsible for the condition that wreaks such havoc for some people, leaving them with debilitating symptoms for years, while causing relatively mild disease for others. Tests for Lyme have high false negative rates, especially early in the infection, so even detecting the disease is challenging.

In a paper published in PLOS Pathogens, an international group of researchers report on the most comprehensive analysis of the Borrelia burgdorferi genome to date, which provides clues about what’s causing more severe forms of the disease, and lays the foundation for developing better diagnostic tests and treatments. The data come from samples painstakingly taken from 299 Lyme patients in the northeastern and midwestern U.S., and central Europe, mostly extracted from skin biopsies of the bullseye-shaped rashes that are a hallmark early sign of infection. The scientists first isolated the bacteria from the biopsied skin samples, then correlated genetic signatures of the bacteria with the patients’ health outcomes. That allowe…

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The Great American Reopening, in 5 Charts

Even a moderately observant UFO monitoring the United States would have noticed, in late March of 2020, that something was seriously amiss. Why are there suddenly so many fewer planes to dodgeคำพูดจาก สล็อตเว็บตรง? What happened to all the cars? Why is it so dark at night?

The COVID-19 pandemic has affected just about every meter of culture and industry except, possibly, the weather. The charts below demonstrate its multifaceted impact, shown against the backdrop of reported COVID-19 cases in the U.S., scaled to fit the range of values in whatever is being graphed.

Let’s start with travel, which, while not yet fully back to normal, is clearly on its way there:

Unfortunately, the novel coronavirus also took a toll on employment—and the nature of how we work, when employed—that resembles transportation figures:

That devastation was also felt in entertainment, as movie theaters shuttered and reopened in limited capacityคำพูดจาก สล็อตเ…

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BGMEA withdraws Edinburgh Woollen Mill claims

However, the group doesn’t appear to have completely stepped back from its earlier claims of money being owed.In a letter, Rubana Huq, President of BGMEA, said that “EWM has paid their suppliers to a considerable extent but a few EWM suppliers still have raw materials which were booked and are still to be lifted”คำพูดจาก สล็อตเว็บตรง. There was some confusion howevr as she gave a dollar figure and said the “outstanding [amount] is less than $28 million”, although it had originally quoted almost £27 million in UK pounds.

EWM added that it wanted “urgent clarification around false figures” and sent a follow-up letter to the group saying its “reckless disregard for accuracy in the disclosures to the media has not only caused damage to the EWM Group but will undoubtedly have a catastrophic knock-on effect on our suppliers and their workforces”. A raft of Western retailers and brands have come in for heavy criticism in recent months as lockdowns and store closures led to order cancellations and some refusals to pay bills.Certain retailers, in…

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Bottega Veneta opens a school in Italy to train the craftsmen of tomorrow

The project includes training activities, workshops and courses, divided between the Kering workshop in Montebello Vicentino, in the province of Vicenza, and a new space in Povolaro Dueville. There are also plans to train 50 students a year in a programme run by 5 Bottega Veneta master craftsmen. The academy will also offer refresher and development programmes for the company’s employees, as well as training with regional partners to promote Veneto’s creativity and pass on the heritage of Made in Italy.

“The Labor and Ingenium Academy is a strategic pillar for preserving Bottega Veneta’s unique know-how,” said Bartolomeo Rongone, CEO of Bottega Veneta. “Craftsmanship and creative excellence are an integral part of our brand and the heritage of our home region, Veneto. With this academy, we are taking the collective ethos, which is at the heart of Bottega Veneta, to an even higher level, building on our rich history of sharing skills and innovation to train the artisans of tomorrow.” The Academy’s first initiative kicked off on October 16 with a seven-week training programme for eight students selected from the university network of Iuav in Venice. Led by Bottega Veneta m…

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China’s textile industry faced with renewed lockdown threats

Last month’s lockdown measures were mostly imposed in smaller cities, but the restrictions’ recent tightening and extension is now affecting major cities too. And this time, the Beijing region has not been spared, with nearly four million people in lockdown in Hebei province, which encircles China’s capital. Tianjin, the port city catering to Beijing, has made testing mandatory for 13 million people this week.A little further east, in the other port city of Dalian, three million people were placed in lockdown on Tuesday, until Sunday. The restrictions are compelling non-essential staff to work from home, while manufacturing companies have to reduce the number of employees active on their production sites. The situation is being closely monitored by Western importers, still affected by the congestion in Chinese ports caused in part by the spring lockdowns.คำพูดจาก สล็อตเว็บตรง

In the southern region of Guangdong, Longhua, a district of Shenzhen with 2.5 million inhabitants, closed down various entertainment venues and wholesale markets on Tuesday, and s…

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Big name brands join Pack4Good eco packaging drive

The initiative was launched in 2019 and those now signed up include fashion and beauty e-tail giant Zalando, plus brands Mango, ba&sh, Ardene, and Nicholas Kirkwood. The new brands bring the total number of Pack4Good partners to 317.Canopy said they’ve all “committed to revolutionising their packaging supply chains to protect vital forests all over the planet”.

The move comes as it also said that every year three billion trees — an area of forest about the size of Germany — are cut down to produce paper packaging. Scientists have urged greater conservation and restoration of forests as vital components in addressing the climate and biodiversity crises.That issue has become more acute as companies have shifted away from plastic packaging and committed to using more paper-based bags and boxes. While consumers have embraced this, few think about the extra eco issues that this shift has created.But now, Nicholas Kirkwood, for instance, said that it “will support approaches and systems to build a future that does not use ancient and endangered forests in the packaging, paper or in man-made cellulosic fabrics, including rayon, viscose, lyocell, modal and other trade…

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Fashion firms dither over instant shopping on the catwalk

Fashion labels may be falling over themselves to court young, smartphone-wielding shoppers, but there’s one millennial-inspired trend that is only catching on slowly: catwalk shows where clothes are available to buy instantly rather than months later.The timing of product drops is becoming an experimental battlefield for luxury goods companies juggling a constant demand for novelty and the lengthy manufacturing cycles needed to make sumptuous fabrics or hand-stitched handbags.คำพูดจาก สล็อตเว็บตรง

Britain’s Mulberry is the latest label to usher in a “see now, buy now” model – cutting out the usual six-month delay in delivering a runway collection to stores – two years after Burberry embraced the idea and set rivals abuzz.Yet it is still far from becoming an industry standard even as brands take other steps to modernise, with more frequent collections rather than just two a year, and questions linger over its benefits.At Mulberry, known for its leather handbags made in southwest England, the strategy should boost sales of full price goods, extending the time …

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Global wearables market growth slows dramatically as consumers seek smarter devices

 The deceleration was driven by a decline of 9.2% in shipments of basic wearables over the period, while shipments of higher priced smart wearables actually increased 28.4% in the quarter, suggesting that consumers are increasingly interested in the expanded capabilities of more technologically advanced products. Furthermore, while watches and wristbands accounted for 95% of all shipments in Q1 2018, other products are rapidly growing in popularity. Shipments of sensor-laden clothing, for example, grew 58.6% compared to Q1 2017. The vast majority of these products are step-counting shoes but companies are offering increasingly diversified sensor-enabled apparel pieces, such as shirts and shorts, primarily with fitness tracking functionalities.

Health-related capabilities are still the focus of many wearables, and technological advances are allowing companies to integrate ever more personalized and precise tools into their products. “Additional sensors, years of underlying data, and improved algorithms are allowing pillars of the industry like Fitbit and Apple to help identify diseases and other health irregularities,” explained Jitesh Ubrani, senior research analyst…

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Amazon says exports from India-based sellers cross $2 billion

Amazon’s “Global Selling” programme was launched in India, a key growth market for the company, in 2015. The programme, also operational in other markets, has helped more than 60,000 Indian sellers export products to 15 Amazon websites, the company said.During a visit to India in January, Amazon boss Jeff Bezos said the U.S. e-commerce company would invest $1 billion in digitising small- and medium-businesses in India and expected to export Indian-made goods worth $10 billion by 2025.คำพูดจาก สล็อตเว็บตรง

Current sales are still a fraction of India’s total exports of goods and services, which are estimated at nearly $530 billion in the financial year that ended on March 31.“It took us three years plus to hit the first billion dollars, today we are able to hit the next billion dollars, 100% growth in the last 18 months,” Gopal Pillai, vice president for seller services at Amazon India, said in a phone interview.Amazon has previously said it has also tied up with Indian banks to provide cheap loans to its small sellers.The biggest market for Amazon�…

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Nordstrom bans fur and exotic animal skins

The policy will be active across the company’s portfolio, including Nordstrom, Nordstrom Rack and Last Chance stores, as well as Nordstrom’s e-commerce sites. The commitment was made in partnership with the Humane Society of the United States.  “As a leading fashion retailer, we’re committed to delivering the best possible service and merchandise for our customers,” said Teri Bariquit, chief merchandising officer at Nordstrom.

Nordstrom bans fur and exotic animal skins

“Delivering on that commitment means continually listening to customer feedback and evolving our product offering to ensure we’re meeting their needs. As part of our ongoing product evolution, we’ve been working with the Humane Society of the United States and recently made the decision to stop offering products made with genuine fur or exotic animal skin in any of our stores or online. Our private label brands haven’t used these materials for years, so extending this policy to all the brands we carry is a natural next step for our busin…

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